Hormone Optimization · Charlotte, NC
Hormone care that reads your whole endocrine system, not one number.
I am Dr. Daniel Tagge, MD. Board-certified family physician, fully certified in Health Optimization Medicine, with the advanced Peptide Hormones certification. I practice in Charlotte and treat North Carolina residents virtually.
No enrollment fee. Cancel anytime.
The approach
The endocrine system is a network. I treat it like one.
Most hormone clinics test one or two hormones, hit a number, write a script. That misses how the system actually works. Thyroid is influenced by cortisol. Sex hormones are influenced by insulin and SHBG. Cortisol is shaped by sleep, training load, and gut inflammation. Reading one hormone in isolation is reading one line of a paragraph.
In my practice, hormone optimization starts with a full read of the system: comprehensive thyroid, sex hormones appropriate to your physiology, cortisol patterning, insulin, IGF-1, and the upstream drivers that shape all of them. From that read, the Plan is specific: what to intervene on, in what order, and how we measure whether it worked.
My advanced Peptide Hormones certification through HOMe gives me the deeper toolkit when it is the right intervention. But hormone therapy is one tool among many. The Plan is built around your physiology, not around a default protocol.
How to start
Hormone care lives inside the membership.
Membership is access to me. I order the hormone work as part of your diagnostic baseline (you pay the lab vendor’s price at cost), interpret it into your written Plan, prescribe as the data calls for it, and refine therapy as your biology responds. No enrollment fee, billed month to month.
Hormone prescribing and ongoing management require ongoing care and are available to North Carolina residents.

Written by
Daniel Tagge, MD
Board-certified family physician. North Carolina’s only physician certified in Health Optimization Medicine. Third-generation physician. NPI 1225562218.
About Dr. TaggeRead deeper
The systems behind hormone work.
How I read the endocrine network, the peptide tools, and the circadian inputs that shape every hormone panel.
Questions
Common questions about hormone optimization.
Hormone replacement treats clinical deficiency. Hormone optimization measures the whole endocrine system against optimal physiology, identifies which hormones are drifting, and intervenes early. Optimization treats the body as a connected system. Thyroid, cortisol, sex hormones, and insulin all influence one another, so the work is to read them together, not in isolation.
It is an advanced certification offered through Health Optimization Medicine (HOMe) covering the clinical use of peptide hormones in optimization care. It builds on the core HOMe certification and is held by a small number of physicians worldwide. I am one of them.
The hormone work in my practice usually includes a comprehensive thyroid panel (TSH, free T3, free T4, reverse T3, thyroid antibodies), sex hormone testing appropriate to your sex and life stage (total and free testosterone, estradiol, progesterone, SHBG, DHEA-S), a four-point cortisol curve when indicated, IGF-1, prolactin, and fasting insulin. The exact panel is built around your symptoms and goals.
Yes, within the Precision Partnership membership, which is an ongoing physician-patient relationship. I prescribe when the testing, your symptoms, and your goals point to it. I do not prescribe blind, and I do not run protocol-based hormone replacement.
Yes. Hormone work in my practice happens inside the Precision Partnership membership, available to North Carolina residents. Care is delivered virtually, with labs drawn locally in Charlotte or wherever you are in NC.
When hormone therapy is indicated, I prescribe what fits your physiology and the evidence. That usually means bioidentical forms, dosed and monitored against the testing rather than against a marketing protocol. The point is the right intervention, not a brand.
Start here
Curious if hormone work is right for you?
A complimentary 30-minute call by phone or video with me. You tell me what is going on. I tell you how I would approach it. You decide if I am the right physician for you.
No enrollment fee. Cancel anytime.