Exposomics.
The cumulative environmental load a person carries can matter for physiology. Some of it can be measured, and I assess it when your history says it is relevant.
The cumulative burden a person carries from diet, chemicals, metals, air, light and the rest of the environment. It can matter for physiology, some of it can be measured, and it is assessed when a history suggests it is relevant.
The system
What it is, and why it matters.
- What it is
- The exposome is the sum of every environmental input your body has had to process. Heavy metals from food, water, and air. Plasticizers from packaging and personal care. Mycotoxins from water-damaged buildings. Pesticide residues. The exposome is not optional. The dose and the detoxification capacity are.
- Why it matters
- The cumulative load of heavy metals, plasticizers, pesticides, and persistent organic pollutants creates measurable dysfunction at the cellular level. Detoxification is not a wellness slogan. It is a real biochemical process with a finite capacity, and modern life routinely exceeds that capacity. When the load wins, every other system pays.
- What I read for
- Total body burden versus mobilized excretion. Which specific compounds are driving symptoms in your case. Your detoxification capacity, especially glutathione status, methylation function, and the activity of liver phase 1 and phase 2 enzymes. The lever changes depending on which of those is rate-limiting.
